British Society for Histocompatibility & Immunogenetics and British Transplantation Society guidelines for the detection and characterisation of clinically relevant antibodies in allotransplantation.

نویسندگان

  • W M Howell
  • A Harmer
  • D Briggs
  • P Dyer
  • S V Fuggle
  • S Martin
  • P Sinnott
  • J Smith
  • C J Taylor
  • R Vaughan
چکیده

Ongoing technological developments in antibody detection and characterisation allowing relative quantitation of HLA-specific antibody levels, combined with crossmatch results, now allow a graded assessment of patient potential donor immunological risk for allotransplantation, rather than a simple 'positive' or 'negative' categorization of crossmatch results. These developments have driven a thorough revision of the British Society for Histocompatibility & Immunogenetics and British Transplantation Society Guidelines for the Detection and Characterisation of Clinically Relevant Antibodies in Allotransplantation. These newly published revised Guidelines contain a number of recommendations as to best practice for antibody detection and crossmatching for the transplantation of a wide range of solid organs and tissues. These recommendations are briefly summarized in this article.

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عنوان ژورنال:
  • International journal of immunogenetics

دوره 37 6  شماره 

صفحات  -

تاریخ انتشار 2010